產品屬性：
產品名稱 | Ras Inhibitory Peptide |
規格 | 500μg、1mg、5mg、10mg |
貨號 | EY-01Y9550 |
Cas No.: 159088-48-9
別名: N/A
化學名: N/A
分子式: C53H91N19O11
分子量: 1170.4
溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: Miscible,PBS (pH 7.2): 10 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Son of sevenless homolog 1 (Sos1) is a guanine nucleotide exchange factor (GEF) that directs the exchange of Ras-GDP to Ras-GTP by binding to SH3 domains of the growth factor receptor-bound protein 2 (Grb2), leading to the activation of ERK. Ras inhibitory peptide is a synthetic peptide that contains the sequence PVPPR, which corresponds to a region within human Sos1 that interacts with an SH3 domain of Grb2. It specifically blocks the interaction of the GEF with Grb2, preventing an interaction that is essential for Ras activation by receptor tyrosine kinases, including epidermal growth factor receptor.
特別提醒公司產品僅供科研使用
