產品屬性：
產品名稱 | MPro Inhibitor 11b |
規格 | 1 mg、5 mg、10 mg |
貨號 | EY-01Y9669 |
Cas No.: 2413716-71-7
別名: N/A
化學名: N/A
分子式: C25H25FN4O4
分子量: 464.5
溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
MPro inhibitor 11b is an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro; IC50 = 0.04 μM in a TR-FRET assay).1 It reduces viral yield in the culture supernatant of SARS-CoV-2-infected Vero E6 cells (EC50 = 0.72 μM). MPro inhibitor 11b also reduces viral RNA copy numbers in the same model when used at concentrations ranging from 1.85 to 50 μM.1.Dai, W., Zhang, B., Jiang, X.-M., et al.Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main proteaseScience368(6497)1331-1335(2020)
特別提醒公司產品僅供科研使用
