產品屬性：
產品名稱 | Mer-NF5003F |
規格 | 1mg、5mg |
貨號 | EY-01Y10080 |
Cas No.: 149598-70-9
別名: N/A
化學名: N/A
分子式: C23H30O5
分子量: 386.5
溶解度: DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Mer-NF5003F is a sesquiterpene originally isolated from Stachybotrys with diverse biological activities.1,2,3 It inhibits avian myeloblastosis virus (AMV) protease (IC50 = 7.8 μM).1 Mer-NF5003F inhibits sialyltransferase 6N (ST6N), ST3O, and ST3N (IC50s = 0.61, 6.7, and 10 μg/ml, respectively), as well as fucosyltransferase (IC50 = 11.3 μg/ml).2 It is active against herpes simplex virus 1 (HSV-1) in vitro (IC50 = 4.32 μg/ml).3 Mer-NF5003F is also active against the multidrug-resistant P. falciparum strain K1 (IC50 = 0.85 μg/ml).|1. Kaneto, R., Dobashi, K., Kojima, I., et al. Mer-NF5003B, E and F, novel sesquiterpenoids as avian myeloblastosis virus protease inhibitors produced by Stachybotrys sp. J. Antibiot. (Tokyo) 47(6), 727-730 (1994).|2. Lin, T.-W., Chang, W.-W., Chen, C.-C., et al. Stachybotrydial, a potent inhibitor of fucosyltransferase and sialyltransferase. Biochem. Biophys. Res. Commun. 331(4), 953-957 (2005).|3. Sawadjoon, S., Kittakoop, P., Isaka, M., et al. Antiviral and antiplasmodial spirodihydrobenzofuran terpenes from the fungus Stachybotrys nephrospora. Planta Med. 70(11), 1085-1087 (2004).
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