產品屬性:
產品名稱 | ML188 |
規格 | 5mg、10mg、50mg |
貨號 | EY-01Y10209 |
Cas No.: 1417700-13-0
別名: N/A
化學名: N/A
分子式: C26H31N3O3

分子量: 433.54
溶解度: DMSO: 250 mg/mL (576.65 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
ML188, a first in class probe, is a selective non-covalent SARS-CoV 3CLpro inhibitor with an IC50 of 1.5 μM. Antiviral activity[1].[1]. Jacobs J, et al. Discovery, synthesis, and structure-based optimization of a series of N-(tert-butyl)-2-(N-arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus (SARS-CoV) 3CL protease. J Med Chem. 2013 Jan 24;56(2):534-46.
特別提醒公司產品僅供科研使用