產品屬性：
產品名稱 | Oritavancin (phosphate) |
規格 | 5mg、10mg、25mg、50mg |
貨號 | EY-01Y10230 |
Cas No.: 192564-14-0
別名: N/A
化學名: N/A
分子式: C86H97Cl3N10O26?2H3PO4
分子量: 1989.1
溶解度: DMF: 0.1 mg/ml,DMSO: 0.1 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Oritavancin is a semisynthetic glycopeptide antibiotic that inhibits the growth of Gram-positive bacteria. It inhibits transglycosylation and transpeptidation in the bacterial cell wall to disrupt membrane integrity. Oritavancin inhibits the growth of clinical isolates from skin and soft-tissue infections, including methicillin-resistant and -susceptible S. aureus (MRSA, MSSA), vancomycin-resistant and -susceptible E. faecium (VREF, VSRF), as well as other staphylococci, streptococci, and enterococci (MIC90s = ≤0.008-0.5 mg/L). Oritavancin inhibits growth of S. aureus in a neutropenic-mouse thigh model of infection (ED50 = 0.95 mg/kg for a single dose). It improves survival in a mouse inhalation model of B. anthracis Ames anthrax when administered prophylactically pre- and postexposure and when administered post symptom development. Formulations containing oritavancin have been used to treat bacterial skin infections.
特別提醒公司產品僅供科研使用
