產品屬性:
產品名稱 | MGR1 |
規格 | 500μg、1mg |
貨號 | EY-01Y10365 |
Cas No.: N/A
別名: N/A
化學名: N/A
分子式: C22H24O5

分子量: 368.4
溶解度: DMF: 30 mg/mL,DMSO: 30 mg/mL,Ethanol: 30 mg/mL
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
MGR1 is a probe that generates reactive oxygen species (ROS).1 Upon activation by esterases, MGR1 produces superoxide in vitro, an effect that is reversed by superoxide dismutase (SOD). MGR1 produces ROS and increases production of oxidized phosphatidylserine species in HEK293T cells. It reduces viability of HEK293T cells (IC50s = 5.1-6.3 μM).References1. Kelkar, D., Ravikumar, G., Mehendale, N., et al. A chemical-genetic screen identifies ABHD12 as an oxidized-phosphatidylserine lipase. Nat. Chem. Biol. 15(2), 169-178 (2019).
特別提醒公司產品僅供科研使用