產品屬性:
產品名稱 | LNP023 |
規格 | 10 mM * 1 mL in DMSO、5mg、10mg、50mg、100mg |
貨號 | EY-01Y10692 |
Cas No.: 1644670-37-0
別名: N/A
化學名: N/A
分子式: C25H30N2O4

分子量: 422.52
溶解度: DMSO: 200 mg/mL (473.35 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
LNP023 is a highly potent factor B (FB) inhibitor with an IC50 value of 10 nM. LNP023 shows direct, reversible, and high-affinity binding to human FB (KD=7.9 nM)[1].[1]. Schubart A, et al. Small-molecule factor B inhibitor for the treatment of complement-mediated diseases. Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):7926-7931.
特別提醒公司產品僅供科研使用