產品屬性：

Cas No.: 1848959-11-4

別名: N/A

化學名: N/A

分子式: C21H24ClFN6O6S

分子量: 542.97

溶解度: DMSO: 83.33 mg/mL (153.47 mM)

儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.

Shipping ConditionEvaluation sample solution : ship with blue ice

All other available size: ship with RT , or blue ice upon request

產品描述：

TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM[1].IC50:0.955 nM (NAE)[1][1]. Yoshimura C, et al. TAS4464, a highly potent and selective inhibitor of NEDD8 activating enzyme, suppresses neddylation and shows antitumor activity in diverse cancer models. Mol Cancer Ther. 2019 May 15.
特別提醒公司產品僅供科研使用