產品屬性：
產品名稱 | Mensacarcin |
規格 | 1 mg |
貨號 | EY-01Y10973 |
Cas No.: 808750-39-2
別名: N/A
化學名: N/A
分子式: C21H24O9
分子量: 420.4
溶解度: DMSO: soluble,Methanol: soluble
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Mensacarcin is a bacterial metabolite that has been found in S. bottropensis and has anticancer activity.1,2 It is cytostatic in the NCI-60 panel of cancer cell lines (mean IC50 = 1.3 μM) and cytotoxic to HepG2, HM02, KATO III, and MCF-7 cells (IC50s = 0.4-50 μM).1 Mensacarcin induces apoptosis in SK-MEL-28 and SK-MEL-5 melanoma cells.21.Maier, S., Pflüger, T., Loesgen, S., et al.Insights into the bioactivity of mensacarcin and epoxide formation by MsnO8Chembiochem15(5)749-756(2014)
2.Plitzko, B., Kaweesa, E.N., and Loesgen, S.The natural product mensacarcin induces mitochondrial toxicity and apoptosis in melanoma cellsJ. Biol. Chem.292(51)21102-21116(2017)
特別提醒公司產品僅供科研使用
