產品屬性：
產品名稱 | Pitavastatin lactone |
規格 | 500μg、1mg、5mg |
貨號 | EY-01Y10972 |
Cas No.: 141750-63-2
別名: N/A
化學名: N/A
分子式: C25H22FNO3
分子量: 403.5
溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml,Ethanol: 10 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Pitavastatin lactone is a major phase 2 metabolite of pitavastatin , an inhibitor of HMG-CoA reductase, that is found in plasma of rats and humans following oral administration., Pitavastatin lactone is formed when pitavastatin undergoes glucuronidation by the UDP-glucuronysyl transferases UGT1A1, UGT1A3, or UGT2B7 to form pitavastatin glucuronide, which then undergoes non-enzymatic conversion to pitavastatin lactone. It can be converted back to pitavastatin via hydrolysis.
特別提醒公司產品僅供科研使用
