產品屬性：
產品名稱 | Taurodeoxychloic Acid sodium hydrate |
規格 | 10mM*1mL in DMSO、10mg、50mg、100mg、200mg |
貨號 | EY-01Y11206 |
Cas No.: 110026-03-4
別名: N/A
化學名: N/A
分子式: C26H47NNaO7S+
分子量: 540.71
溶解度: DMSO: 125 mg/mL (231.61 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Taurodeoxychloic Acid (sodium hydrate) prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation. Taurodeoxychloic Acid (sodium hydrate) is investigated for use in several conditions such as Primary Biliary Cirrhosis (PBC), insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis, and Amyotrophic Lateral Sclerosis[1].
Caspase-12
Taurodeoxychloic Acid (TUDCA) is neuroprotective in a transgenic animal model of Huntington's disease[2].[1]. Xie Q, et al. Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation. Hepatology. 2002 Sep;36(3):592-601.
[2]. Keene CD, et al. Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease. Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10671-6.
特別提醒公司產品僅供科研使用
