產品屬性：
產品名稱 | N4-Acetylcytidine triphosphate sodium |
規格 | 10mM*1mL in Water5mg、50mg、100mg、200mg、500mg |
貨號 | EY-01Y11319 |
Cas No.: N/A
別名: N/A
化學名: N/A
分子式: C11H14N3Na4O15P3
分子量: 613.12
溶解度: H2O: ≥ 250 mg/mL (407.75 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
N4-Acetylcytidine triphosphate sodium is a endogenous nucleoside metabolite from the degradation of tRNA, primes and activates NLRP3 inflammation by inducing HMGB1 expression[1].
NLRP3 Human Endogenous Metabolite
N4-Acetylcytidine (0.3? mM or 1.0? mM) upregulates NF-κB and NLRP3 expression BV2 microglia, and this calls for HMGB1 expression and release[1].[1]. Duan J, et al. N4-acetylcytidine is required for sustained NLRP3 inflammasome activation via HMGB1 pathway in microglia. Cell Signal. 2019 Jun;58:44-52.
特別提醒公司產品僅供科研使用
