產品屬性：
產品名稱 | ML-792 |
規格 | 10mM*1mL in DMSO、5mg、10mg、25mg、50mg、100mg |
貨號 | EY-01Y11380 |
Cas No.: 1644342-14-2
別名: N/A
化學名: N/A
分子式: C21H23BrN6O5S
分子量: 551.41
溶解度: DMSO: 100 mg/mL (181.35 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
ML-792 is a specific small ubiquitin-like modifier (SUMO)-activating enzyme (SAE) inhibitor. ML-792 is a potent and selective inhibitor of SAE/SUMO1 and SAE/SUMO2 in enzymatic assays (IC50s of 3 and 11 nM, respectively) compared with NAE/NEDD8 and UAE/ubiquitin (IC50s of 32 μM and >100 μM, respectively)[1].[1]. He X, et al. Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor. Nat Chem Biol. 2017 Nov;13(11):1164-1171.
特別提醒公司產品僅供科研使用
