產(chǎn)品屬性：
產(chǎn)品名稱 | MSN-125 |
規(guī)格 | 5mg、10mg、25mg、50mg |
貨號 | EY-01Y12308 |
Cas No.: 1592908-16-1
別名: N/A
化學(xué)名: N/A
分子式: C36H38BrN3O6
分子量: 688.61
溶解度: N/A
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
MSN-125 is a potent Bax and Bak oligomerization inhibitor. MSN-125 prevents mitochondrial outer membrane permeabilization (MOMP) with an IC50 of 4 μM. MSN-125 potently inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons, protects primary neurons against glutamate excitotoxicity[1].MSN-125 inhibits tBid/Bax-mediated MOMP in a concentration-dependent manner[1].[1]. Niu X, et al. A Small-Molecule Inhibitor of Bax and Bak Oligomerization Prevents Genotoxic Cell Death and Promotes Neuroprotection. Cell?Chem Biol. 2017 Apr 20;24(4):493-506.e5.
特別提醒公司產(chǎn)品僅供科研使用
