產品屬性：
產品名稱 | Minodronic acid |
規格 | 10mg、50mg、100mg、200mg、500mg |
貨號 | EY-01Y12310 |
Cas No.: 180064-38-4
別名: N/A
化學名: N/A
分子式: C9H12N2O7P2
分子量: 322.15
溶解度: H2O: 5 mg/mL (15.52 mM and warming); DMSO: < 1 mg/mL (insoluble or slightly soluble)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Minodronic acid (YM-529) is a third-generation bisphosphonate that directly and indirectly prevents proliferation, induces apoptosis, and inhibits metastasis of various types of cancer cells. Minodronic acid (YM-529) is an antagonist of purinergic P2X2/3 receptors involved in pain[1][2].P2X2/3[2][1]. Sato K, et al. A third-generation bisphosphonate, minodronic acid (YM529), successfully prevented the growth of bladder cancer in vitro and in vivo. Br J Cancer. 2006 Nov 20;95(10):1354-61.
[2]. Tanaka M, et al. Minodronic acid induces morphological changes in osteoclasts at bone resorption sites and reaches a level required for antagonism of purinergic P2X2/3 receptors. J Bone Miner Metab. 2018 Jan;36(1):54-63.
特別提醒公司產品僅供科研使用
