產品屬性：
產品名稱 | PD-1-IN-22 |
規格 | 100mg、250mg、500mg |
貨號 | EY-01Y12319 |
Cas No.: 2349372-98-9
別名: N/A
化學名: N/A
分子式: C25H25N5O4
分子量: 459.5
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor with an IC50 of 92.3 nM[1].IC50: 92.3 nM (programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction)[1]PD-1-IN-22 dose-dependently elevates IFN-γ secretion in a co-culture model of Hep3B/OS-8/hPD-L1 and CD3 T cells[1].[1]. Qin M, et al. Discovery of [1,2,4]Triazolo[4,3- a]pyridines as Potent Inhibitors Targeting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction. J Med Chem. 2019 May 9;62(9):4703-4715.
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