產品屬性：
產品名稱 | dMCL1-2 |
規格 | 100mg、250mg、500mg |
貨號 | EY-01Y12371 |
Cas No.: 2351218-88-5
別名: N/A
化學名: N/A
分子式: C61H66N10O12S
分子量: 1163.3
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
dMCL1-2 is a potent and selective degrader of myeloid cell leukemia 1 (MCL1) based on PROTAC, which binds to MCL1 with a KD of 30 nM. dMCL1-2 activats the cellular apoptosis machinery by degradation of MCL1[1].KD: 30 nM (MCL1)[1][1]. Papatzimas JW, et al. From Inhibition to Degradation: Targeting the Antiapoptotic Protein Myeloid Cell Leukemia 1 (MCL1). J Med Chem. 2019 Jun 13;62(11):5522-5540.
特別提醒公司產品僅供科研使用
