產品屬性：
產品名稱 | Mcl1-IN-12 |
規格 | 100mg、250mg、500mg |
貨號 | EY-01Y12450 |
Cas No.: 2042211-12-9
別名: N/A
化學名: N/A
分子式: C45H46N4O6S2
分子量: 803
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Mcl1-IN-12 (Compound F) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 μM, respectively. Anti-tumor activity[1].Ki: 0.29 (Mcl-1), 3.1 μM (Bcl-2)[1][1]. Wang M, et al. Design, synthesis, and activity evaluation of selective inhibitors of anti-apoptotic Bcl-2 proteins: The effects on the selectivity of the P1 pockets in the active sites. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5207-5211.
特別提醒公司產品僅供科研使用
