產品屬性：
產品名稱 | Mcl1-IN-8 |
規格 | 5mg、10mg、50mg |
貨號 | EY-01Y12423 |
Cas No.: 678158-55-9
別名: N/A
化學名: N/A
分子式: C22H23N3O2S
分子量: 393.5
溶解度: DMSO: 50 mg/mL (127.06 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Mcl1-IN-8 (Comp8) is a Mcl-1-PUMA interface inhibitor, with a Ki of 0.3 μM. Mcl1-IN-8 (Comp8) exhibits dual activity on reduce PUMA-dependent apoptosis while deactivating Mcl-1-mediated anti-apoptosis in cancer cells[1].[1]. Liu J, et al. Targeting the apoptotic Mcl-1-PUMA interface with a dual-acting compound. Oncotarget. 2017 Apr 20;8(33):54236-54242.
特別提醒公司產品僅供科研使用
