產品屬性:
產品名稱 | NP-12 (TFA) |
規格 | 1mg、5mg、10mg、50mg、100mg |
貨號 | EY-01Y12479 |
Cas No.: N/A
別名: N/A
化學名: N/A
分子式: C144H227F3N40O50

分子量: 3375.63
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
NP-12 (TFA) is a peptide antagonist of the PD-1 signaling pathway, displays equipotent antagonism toward PD-L1 and PD-L2 in rescue of lymphocyte proliferation and effector functions. NP-12 (TFA) exhibits immune activation, excellent antitumor activity, and potential for better management of immune-related adverse events (irAEs)[1].PD-1 signaling pathway[1][1]. Sasikumar PG, et al. A Rationally Designed Peptide Antagonist of the PD-1 Signaling Pathway as an Immunomodulatory Agent for Cancer Therapy. Mol Cancer Ther. 2019 Jun;18(6):1081-1091.
特別提醒公司產品僅供科研使用