產品屬性：
產品名稱 | OXFBD04 |
規格 | 10mM*1mL in DMSO、5mg、10mg、50mg |
貨號 | EY-01Y12681 |
Cas No.: 2231747-03-6
別名: N/A
化學名: N/A
分子式: C17H16N2O3
分子量: 296.32
溶解度: DMSO: ≥ 250 mg/mL (843.68 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
OXFBD04 is a potent and selective BRD4 inhibitor with an IC50 of 166?nM. OXFBD04 is a potent BET bromodomain ligand with additional modest affinity for the CREBBP bromodomain. OXFBD04 has anti-cancer activity[1].[1]. Jennings LE, et al. BET bromodomain ligands: Probing the WPF shelf to improve BRD4 bromodomain affinity and metabolic stability. Bioorg Med Chem. 2018 Jul 15;26(11):2937-2957.
特別提醒公司產品僅供科研使用
