產品屬性：
產品名稱 | Sp-8-bromo-Cyclic AMPS (sodium salt) |
規格 | 500μg、1mg、5mg |
貨號 | EY-01Y12760 |
Cas No.: 1573115-90-8
別名: N/A
化學名: N/A
分子式: C10H10BrN5O5PS?Na
分子量: 446.2
溶解度: DMF: 30 mg/ml,DMSO: 25 mg/ml,Ethanol: 0.5 mg/ml,PBS (pH 7.2): 10 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Sp-8-bromo-cyclic AMPS (Sp-8-bromo-cAMPS) is a cell-permeable, cAMP analog that combines an exocyclic sulfur substitution in the axial position of the cyclophosphate ring with a bromine substitution in the adenine base of cAMP. This configuration pools the structural features of two established cyclic-AMP-dependent protein kinase (PKA) activators, 8-bromo-cAMP and Sp-cAMPS . Sp-8-bromo-cAMPS is a PKA agonist (EC50 = 1.5 μM) with improved lipophilicity and is not readily degraded by cyclic nucleotide phosphodiesterases.
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