產品屬性：
產品名稱 | RMM 46 |
規格 | 10 mg、50 mg |
貨號 | EY-01Y12768 |
Cas No.: 1307896-46-3
別名: N/A
化學名: N/A
分子式: C24H26N4O5
分子量: 450.5
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
MSK/RSK family kinase inhibitor. Exhibits selectivity for RSK2 over NEK2 and PLK1 (IC50s are 12, 530 and 2200 nM, respectively). Inhibits MSK1, MSK2, RSK2 and RSK3 in cellular assays. Reduces CREB phosphorylation in HeLa cells.Miller et al (2013) Electrophilic fragment-based design of reversible covalent kinase inhibitors. J.Am.Chem.Soc. 135 5298 PMID:23540679
特別提醒公司產品僅供科研使用
