產品屬性：
產品名稱 | N-desmethyl Bendamustine |
規格 | 500μg、1mg |
貨號 | EY-01Y13068 |
Cas No.: 41515-13-3
別名: N/A
化學名: N/A
分子式: C15H19Cl2N3O2
分子量: 344.2
溶解度: Acetonitrile:Methanol (1:1): soluble,DMSO: soluble
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
N-desmethyl Bendamustine is an active metabolite of the DNA alkylating agent bendamustine . N-desmethyl Bendamustine is formed through demethylation of the benzimidazole ring in bendamustine by the cytochrome P450 (CYP) isoform CYP1A2. It inhibits proliferation of non-cancerous peripheral blood leukocytes (PBLs; IC50 = 45 μM) and SU-DHL-1, SU-DHL-9, and Daudi lymphoma cells (IC50s = 270, 170, and 120 μM, respectively).
特別提醒公司產品僅供科研使用
