產品屬性:
產品名稱 | 6RK73 |
規格 | 5mg、10mg、50mg、100mg |
貨號 | EY-01Y13062 |
Cas No.: 1895050-66-4
別名: N/A
化學名: N/A
分子式: C13H17N5O2S

分子量: 307.37
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
6RK73 is a covalent irreversible and specific UCHL1 inhibitor with an IC50 of 0.23 μM. 6RK73 shows almost no inhibition of UCHL3 (IC50=236 μM). 6RK73 specifically inhibit UCHL1 activity in breast cancer[1].[1]. Liu S, et al. Deubiquitinase activity profiling identifies UCHL1 as a candidate oncoprotein that promotes TGFβ-induced breast cancer metastasis. Clin Cancer Res. 2019 Dec 19. pii: clincanres.1373.2019.
特別提醒公司產品僅供科研使用