產品屬性：
產品名稱 | Tadalafil-d3 |
規格 | 1 mg、5 mg |
貨號 | EY-01Y13266 |
Cas No.: 960226-55-5
別名: N/A
化學名: N/A
分子式: C22H16D3N3O4
分子量: 392.4
溶解度: DMSO: Soluble,Methanol: Soluble
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Tadalafil-d3 is intended for use as an internal standard for the quantification of tadalafil by GC- or LC-MS. Tadalafil is a potent inhibitor of phosphodiesterase 5 (PDE5; IC50 = 1.2 nM).1 It is selective for PDE5 over PDE1-4 and 7-10 (IC50s = 9.2-280 μM), however, it does also inhibit PDE11 (IC50 = 11 nM). In vivo, tadalafil (10 mg/kg) decreases production of the proinflammatory cytokines TNF-α, IL-1β, and IL-6 and improves renal function in a rat model of ischemia/reperfusion injury.2 It also reduces development of tobacco smoke-induced emphysema and pulmonary hypertension in mice.3 Formulations containing tadalafil have been used to treat erectile dysfunction, pulmonary arterial hypertension, and lower urinary tract dysfunction.
特別提醒公司產品僅供科研使用
