產品屬性：
產品名稱 | Litorin (trifluoroacetate salt) |
規格 | 1 mg、5 mg、10 mg |
貨號 | EY-01Y13352 |
Cas No.: N/A
別名: N/A
化學名: N/A
分子式: C51H68N14O11S·XCF3COOH
分子量: 1085.2
溶解度: Water: soluble
儲存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Litorin is a peptide originally isolated from L. aurea that has diverse biological activities.1,2,3,4 It is an agonist of the gastrin-releasing peptide receptor (GRPR) and the neuromedin B (NMB) receptor in BALB/c 3T3 fibroblasts expressing the human receptors (EC50s = 0.44 and 0.03 nM, respectively) and binds to frog bombesin receptor subtype 4 (BB4) in CHO-K1 cells (Ki = 1.2 nM).2,3 Litorin (10-100 ng/kg) induces contractions of isolated guinea pig gallbladder.4 It decreases food intake in rats when administered at doses ranging from 4 to 128 μg/kg.11.Kulkosky, P.J., and Gibbs, J.Litorin suppresses food intake in ratsLife Sci.31(7)685-692(1982)
2.Uehara, H., González, N., Sancho, V., et al.Pharmacology and selectivity of various natural and synthetic bombesin related peptide agonists for human and rat bombesin receptors differsPeptides32(8)1685-1699(2011)
3.Katsuno, T., Pradhan, T.K., Ryan, R.R., et al.Pharmacology and cell biology of the bombesin receptor subtype 4 (BB4-R)Biochemistry38(22)7307-7320(1999)
4.Endean, R., Erspamer, V., Falconieri Erspamer, G., et al.Parallel bioassay of bombesin and litorin, a bombesin-like peptide from the skin of Litoria aureaBr. J. Pharmacol.55(2)213-219(1975)
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