產品屬性：
產品名稱 | Nesiritide (acetate) |
規格 | 1 mg、5 mg、10 mg |
貨號 | EY-01Y13434 |
Cas No.: 1684439-46-0
別名: N/A
化學名: N/A
分子式: C143H244N50O42S4·C2H4O2
分子量: 3524.1
溶解度: Water: soluble
儲存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Nesiritide is a 32-amino acid natriuretic peptide and recombinant form of human brain natriuretic peptide .1 It increases ex vivo vasorelaxation induced by the calcium ionophore A23187 in porcine hearts isolated from a model of acute coronary occlusion when administered as a 2 μg/kg bolus dose followed by 0.01 μg/kg per minute infusion.2 Formulations containing nesiritide have previously been used in the treatment of congestive heart failure.1.Hobbs, R.E., and Mills, R.M.Therapeutic potential of nesiritide (recombinant b-type natriuretic peptide) in the treatment of heart failureExpert Opin. Investig. Drugs8(7)1063-1072(1999)
2.Lazar, H.L., Bao, Y., Siwik, D., et al.Nesiritide enhances myocardial protection during the revascularization of acutely ischemic myocardiumJ. Card. Surg.24(5)600-605(2009)
特別提醒公司產品僅供科研使用
