產品屬性：
產品名稱 | LX2761 |
規格 | 100mg、250mg、500mg |
貨號 | EY-01Y13560 |
Cas No.: 1610954-97-6
別名: N/A
化學名: N/A
分子式: C32H47N3O6S
分子量: 601.8
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
LX2761 is chemically stable and potent inhibitor against sodium-dependent glucose cotransporter 1 (SGLT1) and SGLT2 in vitro with IC50s of 2.2 nM and 2.7nM for hSGLT1 and hSGLT2, but displays specific SGLT1 inhibition in the gastrointestinal (GI) tract[1].IC50: 2.2 nM (hSGLT1), 2.7nM (hSGLT2)[1][1]. Goodwin NC, et al. Discovery of LX2761, a Sodium-Dependent Glucose Cotransporter 1 (SGLT1) Inhibitor Restrictedto the Intestinal Lumen, for the Treatment of Diabetes. J Med Chem. 2017 Jan 26;60(2):710-721.
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