產品屬性：
產品名稱 | Rac-VU 6008667 |
規格 | 1mg、5mg、10mg、25mg、50mg、100mg |
貨號 | EY-01Y13610 |
Cas No.: 2092917-63-8
別名: N/A
化學名: N/A
分子式: C24H17ClF2N2O2
分子量: 438.85
溶解度: DMSO: 125 mg/mL (284.84 mM); H2O: < 0.1 mg/mL (insoluble)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Rac-VU 6008667 is a selective negative allosteric modulator of muscarinic acetylcholine receptor subtype 5 (M5 NAM) with IC50s of 1.2 μM and 1.6 μM for human M5 and rat M5, respectively. Rac-VU 6008667 has high CNS penetration[1]. M5 NAM: muscarinic acetylcholine receptor subtype 5.[1]. McGowan KM et al, Continued optimization of the M5 NAM ML375: Discovery of VU6008667, an M5 NAM with high CNS penetration and a desired short half-life in rat for addiction studies. Bioorg Med Chem Lett. 2017 Mar 15;27(6):1356-1359.
特別提醒公司產品僅供科研使用
