產品屬性：
產品名稱 | L-Glutamic Acid (ammonium salt) |
規格 | 5 g、10 g、25 g |
貨號 | EY-01Y13626 |
Cas No.: 7558-63-6
別名: N/A
化學名: N/A
分子式: C5H9NO4.NH3
分子量: 164.2
溶解度: PBS (pH 7.2): 10 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
L-Glutamic acid is a non-essential amino acid and the primary excitatory neurotransmitter in the CNS.1 It acts on ionotropic and metabotropic receptors to induce excitatory synaptic transmission and has roles in synaptic plasticity. Excessive release of L-glutamic acid induces excitotoxicity that is associated with various human diseases, including amyotrophic lateral sclerosis (ALS), stroke, Parkinson's disease, Alzheimer's disease, and Huntington's disease.2 Excessive L-glutamic acid release, in its protonated glutamate form, also occurs during seizure activity and contributes to epileptogenesis and seizure-induced brain damage.31.Garattini, S.Glutamic acid, twenty years laterJ. Nutr.130(4S Suppl)901S-909S(2000)
2.Greenamyre, J.T.The role of glutamate in neurotransmission and in neurologic diseaseArch. Neurol.43(10)1058-1063(1986)
3.Barker-Haliski, M., and White, H.S.Glutamatergic mechanisms associated with seizures and epilepsyCold Spring Harb. Perspect. Med.5(8)a022863(2015)
特別提醒公司產品僅供科研使用
