產品屬性：
產品名稱 | Latanoprost ethyl amide |
規格 | 1mg、5mg、10mg |
貨號 | EY-01Y13982 |
Cas No.: 607351-44-0
別名: N/A
化學名: N/A
分子式: C25H39NO4
分子量: 417.6
溶解度: DMF: 30 mg/ml,DMSO: 50 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 200 μ g/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Latanoprost ethyl amide (Lat-NEt) is a latanoprost analog in which the C-1 carboxyl group has been modified to an N-ethyl amide. Prostaglandin esters have been shown to have ocular hypotensive activity. Prostaglandin N-ethyl amides were recently introduced as alternative prostaglandin ocular hypotensive prodrugs. Although it has been claimed that prostaglandin ethyl amides are not converted to the free acids in vivo, studies in our laboratories have shown that bovine and human corneal tissue converts the N-ethyl amides of various prostaglandins to the free acids with a conversion rate of about 2.5 μg/g corneal tissue/hr. Lat-NEt would be expected to show the typical intraocular effects of Latanoprost free acid, but with the much slower hydrolysis pharmacokinetics of the prostaglandin N-amides.
特別提醒公司產品僅供科研使用
