產品屬性：
產品名稱 | LIT-001 |
規格 | 5mg、10mg、25mg、50mg、100mg、200mg、500mg |
貨號 | EY-01Y14156 |
Cas No.: 2245072-21-1
別名: N/A
化學名: N/A
分子式: C30H34F3N7O4S
分子量: 645.7
溶解度: DMSO: 250 mg/mL (387.18 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
LIT-001 is the first nonpeptide oxytocin receptor (OT-R) agonist (EC50=55 nM; Ki=226 nM). LIT-001 improves social interaction in a mouse model of autism[1].In vitro signaling experiments, LIT-001 is a nonbiased OT-R agonist on the two main signaling pathways of this receptor, with minor antagonist effect on V1a and agonist effect on V1b receptors, observed at high concentrations only[1].LIT-001 (10-20 mg/kg; i.p.) alleviates core symptoms in the context of autism spectrum disorders (ASD )[1].
特別提醒公司產品僅供科研使用
