產品屬性：
產品名稱 | REV7/REV3L-IN-1 |
規格 | 100mg、250mg、500mg |
貨號 | EY-01Y14084 |
Cas No.: 1979192-13-6
別名: N/A
化學名: N/A
分子式: C19H21N3O3S
分子量: 371.45
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
REV7/REV3L-IN-1 is a REV7/REV3L interaction inhibitor with an IC50 of 78 μM, which directly binds to REV7 in nuclear magnetic resonance analyses, and inhibits the reactivation of a reporter plasmid containing an interstrand crosslink (ICL) in between the promoter and reporter regions[1].IC50: 78 μM (REV7/REV3L interaction)[1][1]. Actis ML, et al. Identification of the first small-molecule inhibitor of the REV7 DNA repair protein interaction. Bioorg Med Chem. 2016 Sep 15;24(18):4339-4346.
特別提醒公司產品僅供科研使用
