產品屬性：
產品名稱 | LP 922761 |
規格 | 10 mg、50 mg |
貨號 | EY-01Y14308 |
Cas No.: 1454808-95-7
別名: N/A
化學名: N/A
分子式: C21H26N6O3
分子量: 410.47
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Potent AAK1 inhibitor (IC50 values are 4.8 and 7.6 nM in enzyme and cell assays, respectively). Exhibits some selectivity for AAK1 over BIKE, and exhibits no significant activity at opioid, adrenergic α2 or GABAA receptors. Orally bioavailable. Peripherally restricted.Kostich et al (2016) Inhibition of AAK1 kinase as a novel therapeutic approach to treat neuropathic pain. J.Pharmacol.Exp.Ther. 358 371 PMID:27411717
特別提醒公司產品僅供科研使用
