產品屬性:
產品名稱 | MSC1094308 |
規格 | 5mg、10mg、50mg、100mg |
貨號 | EY-01Y14449 |
Cas No.: 2219320-08-6
別名: N/A
化學名: N/A
分子式: C29H29F3N2

分子量: 462.55
溶解度: N/A
儲存條件: N/A
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
MSC1094308 is a reversible and allosteric inhibitor of the type II AAA ATPase human ubiquitin-directed unfoldase (VCP)/p97 and the type I AAA ATPase VPS4B, with IC50 values of 0.71 μM and 7.2 μM for VPS4B and p97, respectively[1].[1]. P?hler R, et al. A Non-Competitive Inhibitor of VCP/p97 and VPS4 Reveals Conserved Allosteric Circuits in Type I and II AAA ATPases. Angew Chem Int Ed Engl. 2018 Feb 5;57(6):1576-1580.
特別提醒公司產品僅供科研使用