產品屬性：
產品名稱 | MRTX1133 |
規格 | 5 mg、10 mg |
貨號 | EY-01Y14644 |
Cas No.: 2621928-55-8
別名: N/A
化學名: N/A
分子式: C33H31F3N6O2
分子量: 600.63
溶解度: N/A
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
MRTX1133 is a highly selective, first-in-class inhibitor of KRAS G12D. MRTX1133 targets the KRAS G12D protein in both active and inactive states. MRTX1133 selectively inhibits KRAS G12D mutant, but not KRAS wild-type, tumor cells[1][2].MRTX1133 demonstrates dose-dependent inhibition of the KRAS pathway tumor regression in G12D mutant tumor models[2].[1]. Xiaolun Wang, et al.Kras g12d inhibitors.WO2021041671A1. [2]. KRAS G12D Inhibitor: MRTX1133. [(accessed on 22 April 2021)];2021 Available online.
特別提醒公司產品僅供科研使用
