產品屬性：
產品名稱 | LC3-mHTT-IN-AN2 |
規格 | 10mM*1mL in DMSO、50mg、100mg、200mg、500mg |
貨號 | EY-01Y14802 |
Cas No.: 7758-73-8
別名: N/A
化學名: N/A
分子式: C15H10O4
分子量: 254.24
溶解度: DMSO: 250 mg/mL (983.32 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
LC3-mHTT-IN-AN2 (Compound AN2) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN2 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons[1].[1]. Li Z, et al. Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds. Nature. 2019 Oct 30.
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