產品屬性：
產品名稱 | Nordeoxycholic Acid |
規格 | 10 mg、50 mg、100 mg、250 mg |
貨號 | EY-01Y14808 |
Cas No.: 53608-86-9
別名: N/A
化學名: N/A
分子式: C23H38O4
分子量: 378.6
溶解度: DMF: 15mg/mL,DMF:PBS (pH 7.2) (1:4): 0.2mg/mL,DMSO: 10mg/mL,Ethanol: 10mg/mL
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Nordeoxycholic acid is a metabolite of the bile acid norcholic acid and a 23-carbon derivative of deoxycholic acid .1 Levels of nordeoxycholic acid are decreased in the liver of rats in a high-fat diet model of non-alcoholic fatty liver disease (NAFLD) and serum levels are lower in men compared with women.2,3 Nordeoxycholic acid has commonly been used as an internal standard for the quantification of bile acids in various sample types by GC- and LC-MS.4,51.Nakatomi, F., Kihira, K., Kuramoto, T., et al.Intestinal absorption and metabolism of norcholic acid in ratsJ. Pharmacobiodyn8(7)557-563(1985)
2.Tang, Y., Zhang, J., Li, J., et al.Turnover of bile acids in liver, serum and caecal content by high-fat diet feeding affects hepatic steatosis in ratsBiochim. Biophys. Acta Mol. Cell Biol. Lipids1864(10)1293-1304(2019)
3.Xie, G., Wang, Y., Wang, X., et al.Profiling of serum bile acids in a healthy Chinese population using UPLC-MS/MSJ. Proteome Res.14(2)850-859(2015)
4.Bergeron, A., Furtado, M., and Garofolo, F.Importance of using highly pure internal standards for successful liquid chromatography/tandem mass spectrometric bioanalytical assaysRapid Commun. Mass Spectrom.23(9)1287-1197(2009)
5.Evrard, E., and Janssen, G.Gas-liquid chromatographic determination of human fecal bile acidsJ. Lipid Res.9(2)226-236(1968)
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