產品屬性：
產品名稱 | Loxoprofen |
規格 | Free Sample (0.1-0.5 mg)、10mM*1mL in DMSO、10mg、50mg、100mg、200mg、500mg、1g |
貨號 | EY-01Y15150 |
Cas No.: 68767-14-6
別名: N/A
化學名: N/A
分子式: C15H18O3
分子量: 246.3
溶解度: DMSO: ≥ 100 mg/mL (406.01 mM)
儲存條件: Store at RT
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Loxoprofen is a non-steroidal anti-inflammatory drug.Target: COXLoxoprofen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group, which also includes ibuprofen and naproxen among others. Loxoprofen is a non-selective cyclooxygenase inhibitor, and works by reducing the synthesis of prostaglandins from arachidonic acid.
COX-1|6.5 μM (IC50, in human whole blood)|COX-2|13.5 μM (IC50, in human whole blood)
[1]. Riendeau D, et al. Evaluation of loxoprofen and its alcohol metabolites for potency and selectivity of inhibition of cyclooxygenase-2. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1201-3.
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