產品屬性：
產品名稱 | ML367 |
規格 | 10mM*1mL in DMSO、5mg、10mg、50mg、100mg、200mg、500mg |
貨號 | EY-01Y15114 |
Cas No.: 381168-77-0
別名: N/A
化學名: N/A
分子式: C19H12F2N4
分子量: 334.32
溶解度: DMSO: ≥ 125 mg/mL (373.89 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization, acts as a probe molecule that has low micromolar inhibitory activity. ML367 blocks DNA repair pathways, suppresses general DNA damage responses including RPA32-phosphorylation and CHK1-phosphorylation in response to UV irradiation[1].ATAD5[1]ML367 (0-40 μM, 16 hours) inhibits FLAG-ATAD5 stabilization in HEK293T cells in the presence or absence of 20 μM 5-FUrd[1]. Western Blot Analysis[1]Cell Line:HEK293T cells[1]. Rohde JM, et al. Discovery of ML367, inhibitor of ATAD5 stabilization. Probe Reports from the NIH Molecular Libraries Program.
特別提醒公司產品僅供科研使用
