產品屬性:
產品名稱 | MDNI-caged-L-glutamate |
規格 | 10 mg |
貨號 | EY-01Y15178 |
Cas No.: 864085-92-7
別名: N/A
化學名: N/A
分子式: C14H16N4O8

分子量: 368.3
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
Rapidly and efficiently releases glutamate when photolysed (350 - 365 nm excitation). Water soluble and stable at neutral pH, and pharmacologically inactive at neuronal glutamate receptors (up to 200 μM). 5.5 times more photosensitive than MNI-caged L-glutamate . Laser activation of MDNI-glu evokes a rapid increase in intracellular Ca2+ concentration in astrocytes.Fedoryak et al (2005) Synthesis of a caged glutamate for efficient one- and two-photon photorelease on living cells. Chem. Commun. (Camb.) 7 3664 PMID:16027904 |Papageorgiou et al (2005) Synthetic and photochemical studies of substituted 1-acyl-7-nitroindolines. Photochem.Photobiol.Sci. 4 887 PMID:16252044 |Popovic et al (2015) Electrical behaviour of dendritic spines as revealed by voltage imaging. Nat.Commun. 6 8436 PMID:26436431
特別提醒公司產品僅供科研使用