產品屬性:
產品名稱 | Loliolide |
規格 | 500 μg、1 mg |
貨號 | EY-01Y15326 |
Cas No.: 2/6/5989
別名: N/A
化學名: N/A
分子式: C11H16O3

分子量: 196.2
溶解度: DMSO: soluble
儲存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
Loliolide is a monoterpene lactone that has been found in P. urinaria and has diverse biological activities.1,2,3,4 It scavenges DPPH and peroxide radicals in cell-free assays when used at concentrations ranging from 62.5 to 250 μM and reduces peroxide-induced apoptosis in Vero cells.1 Loliolide (10 μg/ml) inhibits LPS-induced proliferation of isolated mouse T and B cells.2 It reduces hepatitis C virus (HCV) infectivity in Huh7.5 cells (EC50 = 2.48 μM) and inhibits HCV binding to Huh7.5 cells when used at concentrations of 10 and 50 μM.3 Loliolide also increases A. cephalotes preference for control flakes when applied to test flakes at a concentration of 6.8 mg/g of rye, indicating insect repellent activity.41.Yang, X., Kang, M.-C., Lee, K.-W., et al.Antioxidant activity and cell protective effect of loliolide isolated from Sargassum ringgoldianum subsp. coreanumAlgae26(2)201-208(2011)
2.Okada, N., Shirata, K., Niwano, M., et al.Immunosuppressive activity of a monoterpene from Eucommia ulmoidesPhytochemistry37(1)281-282(1994)
3.Chung, C.-Y., Liu, C.-H., Burnouf, T., et al.Activity-based and fraction-guided analysis of Phyllanthus urinaria identifies loliolide as a potent inhibitor of hepatitis C virus entryAntiviral Res.13058-68(2016)
4.Okunade, A.L., and Wiemer, D.F.(-)-Loliolide, an ant-repellent compound from Xanthoxyllum setulosumJ. Nat. Prod.48(3)472-473(1985)
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