產品屬性：
產品名稱 | Mozavaptan (hydrochloride) |
規格 | 5mg、10mg、50mg、100mg |
貨號 | EY-01Y15443 |
Cas No.: 138470-70-9
別名: N/A
化學名: N/A
分子式: C27H29N3O2?HCl
分子量: 464
溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 25 mg/ml,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Mozavaptan is a benzazepine derivative that antagonizes the binding of arginine vasopressin (AVP) to vasopressin receptors located in the liver (V1; IC50 = 1.2 μM) and kidney (V2; IC50 = 14 nM). At 10-100 μg/kg, mozavaptan can inhibit the antidiuretic action of AVP, promoting aquaresis when administered intravenously to rats. The therapeutic potential of mozavaptan in ectopic antidiuretic hormone syndrome, heart failure, and other complications related to hyponatremia has been studied.
特別提醒公司產品僅供科研使用
