產品屬性:
產品名稱 | N-Oleoyl-L-phenylalanine |
規格 | 1mg、5mg、10mg |
貨號 | EY-01Y16206 |
Cas No.: 136560-78-6
別名: N/A
化學名: N/A
分子式: C27H43NO3

分子量: 429.6
溶解度: DMF: 20 mg/ml,DMSO: 15 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 2 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
N-Oleoyl-L-phenylalanine is an N-acyl amide.1 It increases the oxygen consumption rate (OCR) of mitochondria isolated from mouse brown adipose tissue in a Seahorse assay and decreases oligomycin-induced increases in the mitochondrial membrane potential in C2C12 cells, indicating mitochondrial uncoupling activity, when used at a concentration of 50 μM. N-Oleoyl-L-phenylalanine (30 mg/kg for eight days) reduces food intake and body weight of diet-induced obese mice.|1. Long, J.Z., Svensson, K.J., Bateman, L.A., et al. The secreted enzyme PM20D1 regulates lipidated amino acid uncouplers of mitochondria. Cell 166(2), 1-12 (2016).
特別提醒公司產品僅供科研使用