產品屬性：
產品名稱 | LY2812223 |
規格 | 10mM*1mL in DMSO、1mg、5mg、10mg、50mg |
貨號 | EY-01Y16163 |
Cas No.: 1311385-20-2
別名: N/A
化學名: N/A
分子式: C10H12N4O4S
分子量: 284.29
溶解度: H2O: 50 mg/mL (175.88 mM); DMSO: 28.75 mg/mL (101.13 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
LY2812223 is a highly potent, functionally selective mGlu2 receptor agonist with mGlu2 binding affinity for mGlu2 and mGlu3 (Ki=144 nM and 156 nM, respectively)[1].
mGluR2|144 nM (Ki)|mGluR3|156 nM (Ki)
[1]. Monn JA, et al. Synthesis and Pharmacological Characterization of C4-(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1R,2S,4R,5R,6R)-2-Amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2812223), a Highly Potent, Functionally Selective mGlu2 Receptor Agonist. J Med Chem. 2015 Sep 24;58(18):7526-48.
特別提醒公司產品僅供科研使用
