產品屬性：
產品名稱 | Metyrosine |
規格 | 50mg、100mg、250mg、500mg |
貨號 | EY-01Y16030 |
Cas No.: 672-87-7
別名: N/A
化學名: N/A
分子式: C10H13NO3
分子量: 195.2
溶解度: DMF: <50 μ g/ml,DMSO: <50 μ g/ml,Ethanol: <50 μ g/ml,PBS (pH 7.2): >2 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Metyrosine is an inhibitor of tyrosine hydroxylase. In vivo, metyrosine (200 mg/kg) reduces norepinephrine and dopamine levels in rat brain and disrupts conditioned avoidance behavior in a dose-dependent manner. Metyrosine reduces dopamine transporter knockdown-induced hyperactivity and rearing behavior and increases exploratory behavior in a hole board assay in a mouse model of bipolar disorder mania. It reduces hypertension induced by dexamethasone and cyclosporin in rats. Metyrosine also inhibits norepinephrine production and increases plasma levels of leptin in fasted and fed mice.
特別提醒公司產品僅供科研使用
