產品屬性：
產品名稱 | Norstictic Acid |
規格 | 1mg、5mg |
貨號 | EY-01Y16019 |
Cas No.: 571-67-5
別名: N/A
化學名: N/A
分子式: C18H12O9
分子量: 372.3
溶解度: DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Norstictic acid is a lichen metabolite that has been found in R. farinacea and has antimicrobial and anticancer activities.1,2 It is active against A. hydrophilia, B. subtilis, L. monocytogenes, P. vulgaris, S. faecalis, C. albicans, and C. glabrata (MICs = 0.1-6.7 mM).1 Norstictic acid (1-100 μM) inhibits proliferation, migration, and invasion of MDA-MB-231 cells.2 In vivo, norstictic acid (15 mg/kg, i.p.) reduces tumor growth in an MDA-MB-231/GFP mouse xenograft model.|1. Tay, T., Türk, A.?., Yilmaz, M., et al. Evaluation of the antimicrobial activity of the acetone extract of the lichen Ramalina farinacea and its (+)-usnic acid, norstictic acid, and protocetraric acid constituents. Z. Naturforsch. C J. Biosci. 59(5-6), 384-388 (2004).|2. Ebrahim, H.Y., Elsayed, H.E., Mohyeldin, M.M., et al. Norstictic acid inhibits breast cancer cell proliferation, migration, invasion, and in vivo invasive growth through targeting c-Met. Phytother. Res. 30(4), 557-566 (2016).
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