產品屬性：
產品名稱 | VU6001376 |
規格 | 100mg、250mg、500mg |
貨號 | EY-01Y16450 |
Cas No.: 1968546-34-0
別名: N/A
化學名: N/A
分子式: C18H14F2N6OS
分子量: 400.41
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
VU6001376 is a potent and selective positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4 PAM) with an EC50 of 50.1 nM[1].
mGlu4|50.1 nM (EC50)
[1]. Bollinger SR, et al. Discovery, Structure-Activity Relationship, and Biological Characterization of a Novel Series of 6-((1 H-Pyrazolo[4,3- b]pyridin-3-yl)amino)-benzo[ d]isothiazole-3-carboxamides as Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 4 (mGlu4). J Med Chem. 2019 Jan 10;62(1):342-358.
特別提醒公司產品僅供科研使用
