產品屬性：
產品名稱 | ML-179 |
規格 | 1mg、5mg、10mg、25mg |
貨號 | EY-01Y17004 |
Cas No.: 1883548-87-5
別名: N/A
化學名: N/A
分子式: C21H25F3N4O2
分子量: 422.4
溶解度: DMSO: 10 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
ML-179 is a potent inverse agonist of liver receptor homolog-1 (LRH-1) (IC50 = 320 nM) with maximum efficacy of 40% repression. It is inactive at the related steroidogenic factor-1 transcriptional activator. Through LRH-1, ML-180 alters the expression of haptoglobin and serum amyloid proteins A1 and A4, induces the death of estrogen-receptor negative MDA-MB-231 breast cancer cells, and inhibits the steroidogenic acute regulatory promoter (IC50 = 2.12 μM).
特別提醒公司產品僅供科研使用
